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KMID : 0928320150150030091
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Korean Journal of Health Promotion and Disease Prevention
2015 Volume.15 No. 3 p.91 ~ p.97
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The Relationship between Uric Acid and Homocysteine Levels based on Alcohol-related Facial Flushing
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Kim Eo-Chin
Kim Jong-Sung
Uh Won-Chul
Choi Soo-Young
Lee Sun-Kyung
Jeong Bog-Seon
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Abstract
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Background: This study aimed to determine the correlation between blood uric acid and homocysteine levels, based on alcohol-related facial flushing.
Methods: Among male adults who visited a health examination center of a university hospital located in Daejeon, Korea, for a personal health examination from March 2013 to February 2014, 702 subjects were analyzed including 401 subjects without alcohol-related facial flushing and 301 with facial flushing. Pearson’s correlation and stepwise multivariate linear regression analyses were performed between the log homocysteine levels and other variables including uric acid.
Results: Uric acid showed a significant positive correlation with log homocysteine (γ=0.166, P=0.001) (ß=0.176; P=0.001) in the non-flushing group. In contrast, none of the variables showed any significant correlations with log homocysteine in the flushing group.
Conclusions: Alcohol users not exhibiting alcohol-related facial flushing showed a positive correlation between uric acid and homocysteine levels, whereas those without facial flushing showed no such correlation.
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KEYWORD
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Homocysteine, Uric acid, Flushing, Alcohol drinking
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